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Jordan is a 35-year-old woman who presents with intermittent diarrhoea with cramping that is relieved by defecation. The diarrhoea is not bloody or accompanied by nausea and vomiting. Review of past medical history includes some childhood stomach issues, HTN, and a recent cholecystectomy. She works in the environmental department of a large hotel. She denies alcohol and cigarette. Diagnosis: Irritable Bowel Syndrome (IBS). Discuss the epidemiology of IBS? What is your treatment goals for this patient? Discuss First-line and second-line drug therapy for IBS. Please include pharmacotherapeutic information.