Osteoarthritis Pathophysiology Discussion

Osteoarthritis Pathophysiology Discussion ORDER NOW FOR CUSTOMIZED AND ORIGINAL ESSAY PAPERS ON Osteoarthritis Pathophysiology Discussion All postings must be a minimum of 100 words. Postings less than 100 words will not earn any points. Osteoarthritis Pathophysiology Discussion APA format must be used appropriately, citing a minimum of 1 reference per peer response. MUST use “in-text” citations AND have the reference listed at the end of your post. Both are required to give your author credit for their ideas. ALL documentation is done in APA format. If you do not use the in text citation to give the author credit, you are actually plagiarizing and per the syllabus that will not be allowed. undefined The required references MUST BE SCHOLARLY in nature. A scholarly reference is a textbook and peer-reviewed journal articles ONLY!! Many of your posts included Mayo Clinic, Harvard Med, Medlineplus, cancer.org, etc. These ARE NOT scholarly as they are written for the general public for educational purposes. undefinedTo get the full points you must correct these mistakes in future posts. I take the time to write specific feedback in each of your grading rubrics so please take the time to read the comments even if you are happy with your grade. Please write a response to 1. and 2. Please see attached document for information. attachment_1 All postings must be a minimum of 100 words. Postings less than 100 words will not earn any points. APA format must be used appropriately, citing a minimum of 1 reference per peer response. MUST use “in-text” citations AND have the reference listed at the end of your post. Both are required to give your author credit for their ideas. It is considered plagiarism if you do not give your author credit. ALL documentation is done in APA format. The pathophysiology of Osteoarthritis (OA) consists of joint breakdown of the cartilage, bones, fluid, and synovial lining over the years, causing movement to become difficult and painful. Once the inflammatory chemokines and cytokines are activated, chondrocytes decrease matrix synthesis and increase production of matrix degratory enzymes, stimulating the destruction of cartilage (Liu, 2019). There are many treatments options for OA from self-care to prescriptions, to therapies. This can consist of ice packs, weight loss, staying active, medications, hydrotherapy or physical therapy, stretching, acupuncture, and surgery like an arthroscopy or joint replacement. Cordyceps militaris, an entomopathogenic fungus, has long been used to treat inflammatory diseases in humans. Food and Agricultural Immunology showcases a study which demonstrates that soya-cerebroside (C. militaris extract) reverses IL-1?-induced MMP-1 production in chondrocytes. The ability of soya-cerebroside to antagonize IL-1?-induced cartilage degradation and MMP-1 expression in rat and mouse inflammatory models further adds to the evidence in support of soya-cerebroside in the treatment of OA disease (Liu, 2019). OA is typically a result of aging, but can stem from physical and biochemical factors such as, trauma or injuries, obesity, heredity, other diseases, etc. (Cianflocco, 2011). After an accident as a child, my 24 year old sister was diagnosed with OA. There are times when her knees would get so swollen, they would have to be drained in order to feel some relief. When medication isn’t an option and the pain gets too unbearable, she would need a walker to get around. It can be a roller coaster at times, but she’s been doing pretty well these past few years. (L. Castilleja) Osteoarthritis is the most common form of arthritis, affecting millions of people worldwide. It occurs when the protective cartilage that cushions the ends of your bones wears down over time. Cartilage is a firm, slippery tissue that enables nearly frictionless joint motion. Eventually if the carilage wears down completely, bone will rub on bone. Although osteoarthritis can damage any joint, the disorder most commonly affects joints in your hands, knees, hips, and spine. Knee osteoarthritis is a degenerative joint condition, a leading cause of disability in the United States, and is characterized by low-grade inflammation (Sward, 2012). Ostheoarthritis is a degenerative disease that worsens over time, often resulting in chronic pain. This can’t be reversed, but treatments can reduce pain and help you move better. This can be things such as medications, therapies, or surgical procedures. The type of treatment that will help you the most will be determined by the severity and the location. As of now there is not anyone that I know that has Osteoarthritis.I hope to never have to go through this as this is something that cannot be reversed! (B. Escobedo) If you do not use the in text citation to give the author credit, you are actually plagiarizing and per the syllabus that will not be allowed. The required references MUST BE SCHOLARLY in nature. A scholarly reference is a textbook and peer-reviewed journal articles ONLY!! Many of your posts included Mayo Clinic, Harvard Med, Medlineplus, cancer.org, etc. These ARE NOT scholarly as they are written for the general public for educational purposes. To get the full points you must correct these mistakes in future posts. I take the time to write specific feedback in each of your grading rubrics so please take the time to read the comments even if you are happy with your grade. Osteoarthritis Pathophysiology Discussion Get a 10 % discount on an order above $ 100 Use the following coupon code : NURSING10