Which statements about the modification of chromatin structure in eukaryotes are true?
A.DNA is not transcribed when chromatin is packaged tightly in a condensed form
B.Some forms of chromatin modification can be passed on to future generations of cells
C.Acetylation of histone tails in chromatin allows access to DNA for transcription
D.Acetylation of histone tails is a reversible process
E.Methylation of histone tails in chromatin can promote condensation of the chromatin
F.Deacetylation of histone tails in chromatin loosens the association between nucleosomes and DNA
Expert Answer
(A, C, D, E, F). Histone acetylation (reversible) occurs in chromatins, and it helps create access for transcription of DNA. The condensation of chromatin which makes it to be tightly-packaged, can disrupt this process. Histone methylation promotes condensation. Histone deacetylation breaks the bond between the DNA and nucleosomes in chromatin.
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